Dr Ramaseshan established a prominent school of research in the field of X-ray crystallography in India. His major work relates to anomalous scattering X-rays and neutrons and their application to the understanding of the structure of matter. This technique has been employed by him and others for elucidating the structures of many large molecules, including insulin Recently it has been extended to the study of stregthening mechanisms in solids and to the study of liquid and amorphous states. He was also associated with the development of instrumentation for high and low temperature X-ray crystallography. Dr Ramaseshan has been involved in the application of science to technology. He has also worked on composites and unconventional fabrication processing of materials.