Dr Dutta introduced a new and highly effective laboratory model for the study of human cholera in animals, namely, the use of infant rabbits for the replication of human cholera. This has enabled laboratories throughout the world to undertake studies of cholera even though cholera is not prevalent in their countries. His discovery that Cholera vibrios produces a toxin which causes intense diarrhoea in the animal, is a major breakthrough in cholera research since Koch isolated the vibrio. He has developed a method for evaluating cholera vaccines and antisera, and has discovered a remedy against choleric diarrhoea.